Nucleic Acid Analysis

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In this category you will find application notes and technical bulletins that relate to the use of the GenomeLab™ Products, CEQ™ capillary electrophoresis-based sequencer and the SNPstream® SNP Genotyping System.

Fragment Analysis

• Analysis of 26 Weber Panel Simple Tandem Repeat Polymorphisms Using the CEQ™ 2000 Fragment Analysis System (PDF)
• Automated Binning Process for the Generation of Locus Tags (PDF)
• Highly Precise DNA Sizing on the CEQ™ Fragment Analysis System (PDF)
• The Use of AFLP® Techniques for DNA Fingerprinting in Plants (PDF)

Genetic Analysis

• Bacterial Artificial Chromosome (BAC) End Sequencing Analysis (PDF)

Optimization of Sequencing Methods

• A Rapid and Efficient Method for the Post-Reaction Clean Up of Labeled Dye Terminator Sequencing Products (PDF)
• Improved Sequencing of Plasmids on the CEQ™ 2000 by a Simple Template Preheating Procedure (PDF)
• Post Sequencing Reation Purification in 96-Well Gel Filtration Column Plates (PDF)
• Ultra Fast Separation Methods for the Beckman Coulter CEQ™ 2000 XL DNA Analysis System (PDF)

Sample Tracking and Data Handling

• Call Scores and Quality values: Two Measures of Quality Produced by the CEQ™ Genetic Analysis Systems (PDF)
• Increased Throughput and Sample Tracking Technology with the CEQ™ 8800 Genetic Analysis Systems (PDF)
• Strategies for Automating Data Review (PDF)

SNP Analysis & Mutant Detection

• Automation of Amplification and Primer Extension Chemistries for Beckman Coulter’s GenomeLab™ SNPstream® Genotyping System
• Automating Heterozygote Detection Using the Human P53 Gene as a Model System (PDF)
• Automated, Scalable SNP Analysis the GenomeLab™ SNPstream® Genotyping System (PDF)
• Multiplex mutation Genotyping for Human Diseases; Breast Cancer and Familial Mediterranean Fever (PDF)
• Multiplex SNP Analysis: Screening Factor V R506Q (Leiden) Mutations (PDF)

* All trademarks are the property of their respective owners. Where applicable, the PCR process is covered by patents owned by Roche Molecular Systems, Inc., and F. Hoffmann-LaRoche, Ltd.

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